Stiff-person syndrome

Symptoms include muscle spasms hyper-rigidity debilitating pain and chronic anxiety. Symptoms may include extreme muscle stiffness rigidity and painful spasms in the trunk and limbs severely impairing mobility.

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Stiff person syndrome SPS is a neurological disease with autoimmune features.

. Stiff-person syndrome SPS formerly called stiff-man syndrome is an uncommon disorder characterized by progressive muscle stiffness rigidity and spasm involving the axial muscles resulting in severely impaired ambulation. It is caused by increased muscle activity due to decreased inhibition of the central nervous system CNS that results. Complications may include seizures hallucinations trouble speaking memory problems and problems with hearing.

SPS is labeled as a rare disease. 2 days agoCeline Dion revealed to her fans Thursday she has been diagnosed with stiff-person syndrome a rare neurological disorder that affects about 1 or 2 people per million according to Johns Hopkins Me. Stiff person syndrome spectrum disorders are rare autoimmune and neurological disorders that most often cause muscle stiffness and spasms in the torso and limbs.

Stiff person syndrome SPS is a rare progressive syndrome that affects the nervous system specifically the brain and spinal cord. Muscle spasms can be so violent they can dislocate joints and even break bones. Stiff-person syndrome SPS also known as stiff-man syndrome SMS is a rare neurologic disorder of unclear cause characterized by progressive rigidity and stiffness.

To make an appointment with one of our Restless Legs Syndrome physician specialists please call 410-550-5864. Causes of encephalitis include viruses such as herpes simplex virus. Muscle rigidity sporadic muscle spasms and chronic muscle pain characterize SPS.

The stiffness primarily affects the truncal muscles and is superimposed by spasms resulting in postural deformities. Request an Appointment Adult Neurology. Encephalitis is inflammation of the brain.

Brain herniation is a potentially deadly side effect of very high pressure within the skull that occurs when a part of the brain is squeezed across structures within the skullThe brain can shift across such structures as the falx cerebri the tentorium cerebelli and even through the foramen magnum the hole in the base of the skull through which the spinal cord connects with the brain. Spasms can generate enough force to fracture bone. It is caused by increased muscle activity due to decreased inhibition of the central nervous system CNS that results.

According to a small preliminary study released today a blood treatment called plasmapheresis also known as therapeutic plasma exchange may be a safe way to treat stiff person. SPS is strongly correlated with autoimmune diseases and it is usual to find high titers of antibodie. Stiff-person syndrome SPS formerly called stiff-man syndrome is an uncommon disorder characterized by progressive muscle stiffness rigidity and spasm involving the axial muscles resulting in severely impaired ambulation.

The severity can be variable with symptoms including reduction or alteration in consciousness headache fever confusion a stiff neck and vomiting. Chronic pain impaired mobility and lumbar hyperlordosis are common symptoms. Stiff-person syndrome SPS is a rare and disabling central nervous system disorder with no satisfactory treatment.

But more people are affected than reported due to misdiagnoses.

New Center For Stiff Person Syndrome Johns Hopkins Medicine